Logotipo Fundación Kovacs
  Home   Español   Glossary   Map   Contact   The web of the back   Back Pain Research Network
 The Foundation Medical Research Health Care Promoting Public Health
  Objective and general criteria
  Priority fields of investigation
  Research projects on back disorders
  Research Projects on the System of K-Channels
  Other Lines of Research

Medical Research>> Research projects on back disorders>> Projects on aspects of assessment, diagnosis and prognosis >> The effect of chronification on the quality of life of patients with back pain.

  Projects on risk factors
  Projects on aspects of assessment, diagnosis and prognosis
  - Validation of the Spanish version of the Roland-Morris Scale.
  - Relation between pain intensity and degree of disability and level of quality of life in patients with back pain.
  - Cross-cultural adaptation and validation of a questionnaire on fear and avoidance behaviors due to back pain.
  - The validity of the Spanish version of the Roland-Morris Scale to measure the degree of disability due to low-back pain with sciatica and sciatica without low back pain.
  - Comparative validity of the different components of the EuroQol Scale to determine the quality of life in patients with back pain.
  - The effect of chronification on the quality of life in patients with back pain.
  - Influence of beliefs in the deterioration of quality of life associated with back pain.
  - Determination of the natural course of acute and subacute low back pain.
  - Development of models allowing for the early prediction of the risk of long-term sick leave.
  - Low back function evaluation.
  - Objectification of neck sprain (whiplash).
  - MMICS Study (Musculoskeletal Multinational Inception Cohort Study).
  Projects on treatments
  Projects on clinical practice

  THE EFFECT OF CHRONIFICATION ON THE QUALITY OF LIFE OF PATIENTS WITH BACK PAIN

Title.

The transition from acute to subacute and chronic low back pain: a study based on the determinants of the quality of life and the risk of chronification.

Background.

It is known that acute low back pain and chronic low back pain (that is, pain that lasts more than 90 days) are conceptually different. Contrary to what has been long believed, chronic low back pain does not merely mean the perpetuation of acute low back pain in time, acute and chronic low back pain have different risk factors and respond to different treatments, so that the procedures shown to be effective for each kind of low back pain are different.

In general, the prognosis for chronic low back pain is worse than that for acute. For this reason, it is important to take the necessary measures as soon as possible to prevent the chronification of acute low back pain. Thus, a duration of pain (corresponding to "subacute low back pain") has been defined to try to establish the moment when the appropriate measures should be applied and which because of their cost cannot be applied to all patients with acute low back pain. However, the definition of that period is currently inconsistent and is not based on any scientific study.

On the other hand, an earlier study has shown that the quality of life in patients with low back pain is influenced by the pain's intensity and by the degree of disability (that is, the degree of limitation in daily activities). The influence of these two factors increases over time and practically doubles in two weeks. The first day when the patient sees the doctor for pain, both factors together explain only 27% of the overall quality of life, while 14 days later they explain 58%.

Finally, it is known that the influence of pain and disability on the quality of life doubles in the first 14 days, but it is not known what happens beyond this period. Nor is it known whether this influence is similar in chronic patients. Knowing this would allow for an optimization of treatment strategies, focusing them to improve the quality of life (or to prevent it from getting worse) of patients early and probably more efficiently.

Objective.

To determine the transition calendar from acute low back pain to subacute and chronic, basing it one the evaluation of the determining factors for quality of life and the risk of chronification.

Design.

Prospective, cohort study.

Methodology.

The study was made with a convenience sample of 366 patients who visited their primary care physician for acute or subacute low back pain (that is to say, that lasted under 90 days).

The patients were evaluated on three occasions: the first day they saw the doctor, and 15 and 60 days later. Thus, in the last control the patients who were still subacute were evaluated (that is, those in whom the sum of the period in which they had suffered low back pain before seeing the doctor, plus the two months follow-up, did not reach 90 days) and patients who exceeded that limit.

On each occasion when their situation was evaluated, the patients filled out two scales measuring the pain intensity (one for low back pain and the other for referred or radiated pain), a Roland Morris scale to determine the degree of their disability and a EuroQol questionnaire to evaluate their quality of life.

In the analysis phase, the correlation of the pain, disability and quality of life was evaluated. Additionally, the situation of the patients who became chronic was studied specially (that is to say, those in whom the pain exceeded 90 days duration) and the situation of those in whom disability and quality of life did not improve over the follow-up period, in order to determine the cut-off point for pain duration at which the risk of chronification is greater.

Participants, along with the Foundation's Science Department.

106 researchers from 40 Primary Care centers and Primary Care Research Units in Badajoz, Baleares, Bilbao, Burgos, Cáceres, Cuenca, Guadalajara, Huesca, Madrid, Murcia, Palencia, Valencia, as well as the Unit of Clinical Biostatistics at the Hospital Ramón y Cajal, Madrid; all of them part of the Spanish Network of Researchers in Back Disorders.

The study was funded by the Kovacs Foundation.

Status.

Data collection has concluded and data is currently being analyzed.

subir subir
© Fundación Kovacs 2005