TRANSPORT
VELOCITY IN THE HUMAN
Title.
Study of the velocity of the subcutaneous
migration of sodium pertechnetate in the human being.
Background.
The studies
already made have shown that Tc-99m, in the form of sodium
pertechnetate, hypodermically injected in the human has a
migration pattern of the same characteristics as that in a
research animal. However, the velocity at which the substances
travel through the K-channels in the human being is still
unknown.
Objective.
To define the speed at which the sodium pertechnetate
moves through the K-channels in the human being.
Methodology.
A total of 50 experiments were performed
on 10 healthy subjects (five experiments per subject) who
were informed, verbally and in writing, about the nature of
the study and who signed a written informed consent. The experiments
consisted of a subcutaneous injection, 4 mm deep, of 300 m
Cu of Tc-99m, contained in a volume of 0.125 ml, in a point
situated in the posterior part of the wrist and defined by
its low electrical resistance in comparison with the subject's
ear.
A radioactive ring had been prepared beforehand and placed
on the subject's forearm, 20 cms from the point of injection.
The time the isotope took in being transported to the spot
where the ring is located was measured. This was the fundamental
variable, which determined migration speed; other variables
collected include gender, age, size, weight, wrist diameter,
and blood pressure (taken before and after the experiments).
In these experiments, an Elscint Apex SP-6HR tomogrammacamera
was used, connected on-line to an Elscint Apex SPX computer
with software version 5.3.
Participants, along with the Foundation's
Science Department.
Department of Nuclear Medicine at the Son
Dureta Hospital (Palma de Mallorca).
Funded in full by the Kovacs Foundation.
Status.
On hold, until the funds needed to finance
its resumption become available.
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